SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03616

Signal sequence   MHGSCSFLMLLLPLLLLLVATTGPVGA

Length  27

Organism  Homo sapiens (Human)

UniProt ID  Q6UXB8,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03616.cif

Structure  SPKB03616.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2768.47004

Aliphatic index  158.8888889

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  911.94

Aromaticity  0.037037037

Average rotatable bonds  3.185185185

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  36

X logP energy  -3.9329

Hydropathy 



Literature Information


Title  Identification, purification and characterization of a novel human blood protein with binding affinity for prostate secretory protein of 94 amino acids.

DOI  10.1042/BJ20040290,

Publication Year  2005

PubMed ID  15344909,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.