SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03606

Signal sequence   MRLLVLSSLLCILLLCFSIFSTEG

Length  24

Organism  Homo sapiens (Human)

UniProt ID  Q6UWK7,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03606.cif

Structure  SPKB03606.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2672.33804

Aliphatic index  174.5833333

Isoelectric point  6.135737489

Charge (pH=7)   -0.124193321

Topological polar surface area  932.97

Aromaticity  0.083333333

Average rotatable bonds  3.708333333

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  35

X logP energy  -4.12673

Hydropathy 



Literature Information


Title  CSBF/C10orf99, a novel potential cytokine, inhibits colon cancer cell growth through inducing G1 arrest.

DOI  10.1038/srep06812,

Publication Year  2014

PubMed ID  25351403,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.