SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03602

Signal sequence   MLPPMALPSVSWMLLSCLILLCQVQG

Length  26

Organism  Homo sapiens (Human)

UniProt ID  Q6UW15,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03602.cif

Structure  SPKB03602.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2844.60104

Aliphatic index  146.1538462

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  927.11

Aromaticity  0.038461538

Average rotatable bonds  3.384615385

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  37

X logP energy  -3.2802

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.