SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03600

Signal sequence   MNVFFMFSLLFLAALGSC

Length  18

Organism  Gloydius halys (Chinese water mocassin) (Agkistrodon halys)

UniProt ID  Q6STF1,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03600.cif

Structure  SPKB03600.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2011.48554

Aliphatic index  113.8888889

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  641.57

Aromaticity  0.222222222

Average rotatable bonds  3.5

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  -1.5817

Hydropathy 



Literature Information


Title  Purification, partial characterization, crystallization and structural determination of AHP-LAAO, a novel L-amino-acid oxidase with cell apoptosis-inducing activity from Agkistrodon halys pallas venom.

DOI  10.1107/S0907444904000046,

Publication Year  2004

PubMed ID  15103157,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.