SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03594

Signal sequence   MSSAFLLLACALVISVHA

Length  18

Organism  Aplysia californica (California sea hare)

UniProt ID  Q6IWZ0,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03594.cif

Structure  SPKB03594.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1846.27634

Aliphatic index  162.7777778

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  647.39

Aromaticity  0.055555556

Average rotatable bonds  3.222222222

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -3.8697

Hydropathy 



Literature Information


Title  Cloning, characterization and expression of escapin, a broadly antimicrobial FAD-containing L-amino acid oxidase from ink of the sea hare Aplysia californica.

DOI  10.1242/jeb.01795,

Publication Year  2005

PubMed ID  16155232,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.