SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03593

Signal sequence   MRRCGRHSGPPSLLLLLLLLPPLLLSVPGAYA

Length  32

Organism  Rattus norvegicus (Rat)

UniProt ID  Q6IUU3,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03593.cif

Structure  SPKB03593.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3425.24364

Aliphatic index  149.375

Isoelectric point  11.05985778

Charge (pH=7)   3.026058326

Topological polar surface area  1216.77

Aromaticity  0.03125

Average rotatable bonds  3.25

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  43

X logP energy  -6.58109

Hydropathy 



Literature Information


Title  Rat seminal vesicle FAD-dependent sulfhydryl oxidase. Biochemical characterization and molecular cloning of a member of the new sulfhydryl oxidase/quiescin Q6 gene family.

DOI  10.1074/jbc.M010933200,

Publication Year  2001

PubMed ID  11278790,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.