SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03587

Signal sequence   MKSMLVVTISVWLILAPTSTWA

Length  22

Organism  Phytolacca heterotepala (Mexican pokeweed)

UniProt ID  Q6EH50,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03587.cif

Structure  SPKB03587.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2448.01994

Aliphatic index  137.2727273

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  844.61

Aromaticity  0.090909091

Average rotatable bonds  3.409090909

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -3.4739

Hydropathy 



Literature Information


Title  Isolation and characterization of heterotepalins, type 1 ribosome-inactivating proteins from Phytolacca heterotepala leaves.

DOI  10.1016/j.phytochem.2006.12.002,

Publication Year  2007

PubMed ID  17258249,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.