General Information
SPKB ID SPKB03583
Signal sequence MARQGCLGSFQVISLFTFAISVNICLG
Length 27
Organism Rattus norvegicus (Rat)
UniProt ID Q64610,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 2XRG,
Predicted Structure ID SPKB03583.cif
Physicochemical Information
Molecular weight 2876.44254
Aliphatic index 115.5555556
Isoelectric point 8.231408964
Charge (pH=7) 0.874031556
Topological polar surface area 1092.01
Aromaticity 0.111111111
Average rotatable bonds 3.481481481
Number of hydrogen bond donors 40
Number of hydrogen bond acceptors 39
X logP energy -10.10613
Hydropathy 
Literature Information
Title Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D.
DOI 10.1242/jcs.02438,
Publication Year 2005
PubMed ID 15985467,
Patent ID NA,
