SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03580

Signal sequence   MSSSCSGLTRVLVAVATALVSSS

Length  23

Organism  Mus musculus (Mouse)

UniProt ID  Q64385,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03580.cif

Structure  SPKB03580.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2226.58864

Aliphatic index  114.3478261

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  947.49

Aromaticity  0

Average rotatable bonds  3.130434783

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  36

X logP energy  -14.82883

Hydropathy 



Literature Information


Title  Recombinant soluble interleukin-11 (IL-11) receptor alpha-chain can act as an IL-11 antagonist.

DOI  NA,

Publication Year  1997

PubMed ID  9373251,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.