SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03578

Signal sequence   MAATVRRQRPRRLLCWALVAVLLADLLALSDT

Length  32

Organism  Rattus norvegicus (Rat)

UniProt ID  Q63617,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03578.cif

Structure  SPKB03578.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3593.35614

Aliphatic index  143.4375

Isoelectric point  11.8984296

Charge (pH=7)   2.936885995

Topological polar surface area  1460.3

Aromaticity  0.03125

Average rotatable bonds  3.65625

Number of hydrogen bond donors  55

Number of hydrogen bond acceptors  46

X logP energy  -10.91845

Hydropathy 



Literature Information


Title  Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain.

DOI  10.1074/jbc.271.9.5025,

Publication Year  1996

PubMed ID  8617779,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.