SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03577

Signal sequence   MPPRAPPAPGPRPPPRAAGRHGLSPLAPRPWRWLLLLALPAVCSA

Length  45

Organism  Rattus norvegicus (Rat)

UniProt ID  Q63415,

Motif  1..45



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03577.cif

Structure  SPKB03577.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4766.74714

Aliphatic index  84.88888889

Isoelectric point  12.80106694

Charge (pH=7)   6.026898807

Topological polar surface area  1701.57

Aromaticity  0.044444444

Average rotatable bonds  2.822222222

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  57

X logP energy  -11.99688

Hydropathy 



Literature Information


Title  Peptidomics for Studying Limited Proteolysis.

DOI  10.1021/acs.jproteome.5b00820,

Publication Year  2015

PubMed ID  26479776,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.