SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03576

Signal sequence   MPPGGSGQGGCPRRPPALAGPLPPPPPPPPLPLLLGLLLLLGAAEG

Length  46

Organism  Rattus norvegicus (Rat)

UniProt ID  Q63376,

Motif  1..46



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03576.cif

Structure  SPKB03576.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4408.33224

Aliphatic index  101.9565217

Isoelectric point  8.549845238

Charge (pH=7)   0.937778084

Topological polar surface area  1465.39

Aromaticity  0

Average rotatable bonds  2.543478261

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  54

X logP energy  -10.59136

Hydropathy 



Literature Information


Title  Conserved domain structure of beta-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins.

DOI  NA,

Publication Year  1994

PubMed ID  8163501,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.