SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03575

Signal sequence   MYQRMLRCGAELGSPGGGSSGGAGGRLALLWIVPLTLSGLLGVAWG

Length  46

Organism  Rattus norvegicus (Rat)

UniProt ID  Q63373,

Motif  1..46



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03575.cif

Structure  SPKB03575.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4587.39884

Aliphatic index  106.0869565

Isoelectric point  9.498709097

Charge (pH=7)   1.936924358

Topological polar surface area  1774.29

Aromaticity  0.065217391

Average rotatable bonds  3.195652174

Number of hydrogen bond donors  65

Number of hydrogen bond acceptors  61

X logP energy  -17.24149

Hydropathy 



Literature Information


Title  Conserved domain structure of beta-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins.

DOI  NA,

Publication Year  1994

PubMed ID  8163501,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.