SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03568

Signal sequence   MVGRVQPDRKQLPLVLLRLLCLLPTGLP

Length  28

Organism  Rattus norvegicus (Rat)

UniProt ID  Q62813,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03568.cif

Structure  SPKB03568.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3139.94134

Aliphatic index  156.4285714

Isoelectric point  11.37963925

Charge (pH=7)   2.9361511

Topological polar surface area  1169.29

Aromaticity  0

Average rotatable bonds  3.607142857

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  39

X logP energy  -5.85339

Hydropathy 



Literature Information


Title  The limbic system-associated membrane protein is an Ig superfamily member that mediates selective neuronal growth and axon targeting.

DOI  10.1016/0896-6273(95)90034-9,

Publication Year  1995

PubMed ID  7646886,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.