SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03565

Signal sequence   MAPDISCFFLVALFLASCRA

Length  20

Organism  Mus musculus (Mouse)

UniProt ID  Q62192,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03565.cif

Structure  SPKB03565.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2175.64984

Aliphatic index  112.5

Isoelectric point  6.064584924

Charge (pH=7)   -0.12552196

Topological polar surface area  747.09

Aromaticity  0.15

Average rotatable bonds  3.3

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -3.90093

Hydropathy 



Literature Information


Title  RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family.

DOI  NA,

Publication Year  1995

PubMed ID  7897216,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.