SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03561

Signal sequence   MAVALGRAPRSLPLLLTLLLLLLLRMSPSWS

Length  31

Organism  Mus musculus (Mouse)

UniProt ID  Q61789,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03561.cif

Structure  SPKB03561.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3403.27784

Aliphatic index  170

Isoelectric point  12.801071

Charge (pH=7)   2.997974365

Topological polar surface area  1212.59

Aromaticity  0.032258065

Average rotatable bonds  3.483870968

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  42

X logP energy  -5.26879

Hydropathy 



Literature Information


Title  Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.

DOI  10.1042/0264-6021:3620213,

Publication Year  2002

PubMed ID  11829758,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.