SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03560

Signal sequence   MARIPRCDFLRPPGIYYLITSLLAGLFLPPAIA

Length  33

Organism  Mus musculus (Mouse)

UniProt ID  Q61738,

Motif  1..33



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03560.cif

Structure  SPKB03560.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3660.48274

Aliphatic index  130.3030303

Isoelectric point  9.324265969

Charge (pH=7)   1.934745305

Topological polar surface area  1254.49

Aromaticity  0.121212121

Average rotatable bonds  3.272727273

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  44

X logP energy  -4.05119

Hydropathy 



Literature Information


Title  Laminin-binding integrin alpha 7 beta 1: functional characterization and expression in normal and malignant melanocytes.

DOI  10.1091/mbc.2.10.805,

Publication Year  1991

PubMed ID  1839357,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.