SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03558

Signal sequence   MIAMLTVLLYLALILEPRTAVQA

Length  23

Organism  Mus musculus (Mouse)

UniProt ID  Q61450,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03558.cif

Structure  SPKB03558.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2544.19264

Aliphatic index  178.2608696

Isoelectric point  6.403313374

Charge (pH=7)   -0.001094303

Topological polar surface area  897.71

Aromaticity  0.043478261

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -2.05983

Hydropathy 



Literature Information


Title  Molecular cloning of gp49, a cell-surface antigen that is preferentially expressed by mouse mast cell progenitors and is a new member of the immunoglobulin superfamily.

DOI  NA,

Publication Year  1991

PubMed ID  1714901,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.