SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03555

Signal sequence   MLLLQALLFLLILPSHA

Length  17

Organism  Mus musculus (Mouse)

UniProt ID  Q60994,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03555.cif

Structure  SPKB03555.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1906.44334

Aliphatic index  218.2352941

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  612.13

Aromaticity  0.058823529

Average rotatable bonds  3.588235294

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  22

X logP energy  1.3354

Hydropathy 



Literature Information


Title  Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity.

DOI  10.1074/jbc.M200601200,

Publication Year  2002

PubMed ID  11912203,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.