SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03551

Signal sequence   MLRRRGSPGMGVHVGAALGALWFCLTGA

Length  28

Organism  Homo sapiens (Human)

UniProt ID  Q5ZPR3,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03551.cif

Structure  SPKB03551.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2885.46204

Aliphatic index  90.71428571

Isoelectric point  12.19926532

Charge (pH=7)   3.02690874

Topological polar surface area  1110.86

Aromaticity  0.071428571

Average rotatable bonds  3.25

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  38

X logP energy  -10.11009

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.