SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03549

Signal sequence   MSKLLILLLLSLVASIFS

Length  18

Organism  Dictyostelium discoideum (Social amoeba)

UniProt ID  Q5XM24,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03549.cif

Structure  SPKB03549.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1961.51734

Aliphatic index  216.6666667

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  664.96

Aromaticity  0.055555556

Average rotatable bonds  3.722222222

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -1.1753

Hydropathy 



Literature Information


Title  A secreted factor represses cell proliferation in Dictyostelium.

DOI  10.1242/dev.02032,

Publication Year  2005

PubMed ID  16176950,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.