General Information
SPKB ID SPKB03548
Signal sequence MAAASAGATRLLLLLLMAVAAPSRA
Length 25
Organism Homo sapiens (Human)
UniProt ID Q5UCC4,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6WW7,
Predicted Structure ID SPKB03548.cif
Physicochemical Information
Molecular weight 2440.00374
Aliphatic index 141.2
Isoelectric point 12.50010931
Charge (pH=7) 1.997977677
Topological polar surface area 937.42
Aromaticity 0
Average rotatable bonds 3.12
Number of hydrogen bond donors 34
Number of hydrogen bond acceptors 33
X logP energy -8.31906
Hydropathy
Literature Information
Title Structural basis for membrane insertion by the human ER membrane protein complex.
Publication Year 2020
PubMed ID 32439656,
Patent ID NA,