SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03546

Signal sequence   MKRVSRRAFLRRLGVGVAATAA

Length  22

Organism  Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

UniProt ID  Q5SK82,

Motif  1..22



Activity Information


Pathway  Tat

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  2ZZV,

Predicted Structure ID  SPKB03546.cif

Structure  SPKB03546.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2386.89374

Aliphatic index  97.72727273

Isoelectric point  13.10475986

Charge (pH=7)   5.997672709

Topological polar surface area  1050.4

Aromaticity  0.045454545

Average rotatable bonds  3.681818182

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  32

X logP energy  -11.18415

Hydropathy 



Literature Information


Title  Crystal structure of a periplasmic substrate-binding protein in complex with calcium lactate.

DOI  10.1016/j.jmb.2009.07.043,

Publication Year  2009

PubMed ID  19631222,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.