General Information
SPKB ID SPKB03544
Signal sequence MKKFGAVVLALFLVGLMAGSVLA
Length 23
Organism Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
UniProt ID Q5JIZ5,
Motif 1..23
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Extracellular environment
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03544.cif
Physicochemical Information
Molecular weight 2335.97834
Aliphatic index 152.6086957
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 775.79
Aromaticity 0.086956522
Average rotatable bonds 3.391304348
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 29
X logP energy -1.8659
Hydropathy 
Literature Information
Title Crystal structure of a subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis: requirement of a C-terminal beta-jelly roll domain for hyperstability.
DOI 10.1016/j.jmb.2010.05.064,
Publication Year 2010
PubMed ID 20595040,
Patent ID NA,
