SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03543

Signal sequence   MAAVRGVRVVGTSPGLLLGRGMRAFLLLLCLAARGGA

Length  37

Organism  Rattus norvegicus (Rat)

UniProt ID  Q5I0E7,

Motif  1..37



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03543.cif

Structure  SPKB03543.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3724.59504

Aliphatic index  131.8918919

Isoelectric point  12.67614575

Charge (pH=7)   4.935993027

Topological polar surface area  1452.09

Aromaticity  0.027027027

Average rotatable bonds  3.324324324

Number of hydrogen bond donors  55

Number of hydrogen bond acceptors  48

X logP energy  -12.74255

Hydropathy 



Literature Information


Title  gp25L/emp24/p24 protein family members of the cis-Golgi network bind both COP I and II coatomer.

DOI  10.1083/jcb.140.4.751,

Publication Year  1998

PubMed ID  9472029,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.