SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03541

Signal sequence   MKSLLALVAGNLVTAVSG

Length  18

Organism  Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)

UniProt ID  Q5B1W7,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03541.cif

Structure  SPKB03541.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1744.12284

Aliphatic index  151.6666667

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  687.82

Aromaticity  0

Average rotatable bonds  3.222222222

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -6.7623

Hydropathy 



Literature Information


Title  A seven-transmembrane methyltransferase catalysing N-terminal histidine methylation of lytic polysaccharide monooxygenases.

DOI  10.1038/s41467-023-39875-7,

Publication Year  2023

PubMed ID  37452022,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.