SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03538

Signal sequence   MLFKSFVTFTVLANALAAPLAHQHHQHKEEKR

Length  32

Organism  Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

UniProt ID  Q59XX2,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Cell wall

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03538.cif

Structure  SPKB03538.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3701.30994

Aliphatic index  82.5

Isoelectric point  10.5008504

Charge (pH=7)   2.364282496

Topological polar surface area  1475.87

Aromaticity  0.09375

Average rotatable bonds  3.8125

Number of hydrogen bond donors  50

Number of hydrogen bond acceptors  50

X logP energy  -11.58623

Hydropathy 



Literature Information


Title  Purification and biochemical characterization of a 65-kilodalton mannoprotein (MP65), a main target of anti-Candida cell-mediated immune responses in humans.

DOI  10.1128/iai.64.7.2577-2584.1996,

Publication Year  1996

PubMed ID  8698482,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.