SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03536

Signal sequence   MIPSTAAAALLTLTAGVALAHPGCGGQEIGRRNVGGPMVYRRDVTDEASAA

Length  51

Organism  Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)

UniProt ID  Q55U20,

Motif  1..51



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03536.cif

Structure  SPKB03536.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5094.81404

Aliphatic index  88.23529412

Isoelectric point  7.358941813

Charge (pH=7)   0.030498229

Topological polar surface area  2145.22

Aromaticity  0.019607843

Average rotatable bonds  3.176470588

Number of hydrogen bond donors  76

Number of hydrogen bond acceptors  73

X logP energy  -26.59282

Hydropathy 



Literature Information


Title  Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T cell responses to Cryptococcus neoformans.

DOI  10.1073/pnas.181331398,

Publication Year  2001

PubMed ID  11504924,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.