SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03535

Signal sequence   MRGLAKLFFLSCSFVSLVSS

Length  20

Organism  Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)

UniProt ID  Q55P57,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03535.cif

Structure  SPKB03535.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2192.66254

Aliphatic index  112

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  805.29

Aromaticity  0.15

Average rotatable bonds  3.6

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -6.47803

Hydropathy 



Literature Information


Title  Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccase.

DOI  10.1128/jb.176.3.656-664.1994,

Publication Year  1994

PubMed ID  8300520,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.