SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03523

Signal sequence   MHPLPSVALLSAIGAVA

Length  17

Organism  Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)

UniProt ID  Q4WBS1,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03523.cif

Structure  SPKB03523.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1647.00864

Aliphatic index  149.4117647

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  580.48

Aromaticity  0

Average rotatable bonds  2.823529412

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  22

X logP energy  -3.9216

Hydropathy 



Literature Information


Title  Purification and characterization of two forms of endo-beta-1,4-mannanase from a thermotolerant fungus, Aspergillus fumigatus IMI 385708 (formerly Thermomyces lanuginosus IMI 158749).

DOI  10.1016/j.bbagen.2004.06.022,

Publication Year  2004

PubMed ID  15541293,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.