SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03519

Signal sequence   MKRHILATVIASLVAAPAMALA

Length  22

Organism  Salmonella dublin

UniProt ID  Q4VYA5,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03519.cif

Structure  SPKB03519.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2248.81694

Aliphatic index  146.8181818

Isoelectric point  11.65178972

Charge (pH=7)   2.088595045

Topological polar surface area  822.69

Aromaticity  0

Average rotatable bonds  3.272727273

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -4.99553

Hydropathy 



Literature Information


Title  Structural and functional evolution of transthyretin and transthyretin-like proteins.

DOI  10.1002/prot.21033,

Publication Year  2006

PubMed ID  16783790,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.