SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03517

Signal sequence   MGRFISVSFGLLVVFLSLSGTGAG

Length  24

Organism  Daboia siamensis (Eastern Russel's viper) (Daboia russelii siamensis)

UniProt ID  Q4PRD2,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03517.cif

Structure  SPKB03517.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2415.87614

Aliphatic index  121.6666667

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  895.67

Aromaticity  0.125

Average rotatable bonds  3.25

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -7.98143

Hydropathy 



Literature Information


Title  New insights into the functions and N-glycan structures of factor X activator from Russell's viper venom.

DOI  10.1111/j.1742-4658.2008.06540.x,

Publication Year  2008

PubMed ID  18616470,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.