SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03516

Signal sequence   MGRFISVSFGCLVVFLSLSGTEA

Length  23

Organism  Daboia siamensis (Eastern Russel's viper) (Daboia russelii siamensis)

UniProt ID  Q4PRD1,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03516.cif

Structure  SPKB03516.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2420.86724

Aliphatic index  110

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  903.87

Aromaticity  0.130434783

Average rotatable bonds  3.391304348

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -7.98053

Hydropathy 



Literature Information


Title  Coagulation factor X activating enzyme from Russell's viper venom (RVV-X). A novel metalloproteinase with disintegrin (platelet aggregation inhibitor)-like and C-type lectin-like domains.

DOI  NA,

Publication Year  1992

PubMed ID  1629211,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.