SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03508

Signal sequence   MRLVAKLLYLAVLAICGLGIHGALTHPR

Length  28

Organism  Sambucus nigra (European elder)

UniProt ID  Q41358,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03508.cif

Structure  SPKB03508.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3000.74644

Aliphatic index  160.3571429

Isoelectric point  10.45701669

Charge (pH=7)   3.116675695

Topological polar surface area  1087.87

Aromaticity  0.035714286

Average rotatable bonds  3.464285714

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  38

X logP energy  -4.70606

Hydropathy 



Literature Information


Title  The NeuAc(alpha-2,6)-Gal/GalNAc-binding lectin from elderberry (Sambucus nigra) bark, a type-2 ribosome-inactivating protein with an unusual specificity and structure.

DOI  10.1111/j.1432-1033.1996.00128.x,

Publication Year  1996

PubMed ID  8631319,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.