SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03507

Signal sequence   MKMKVLEVVGLAISIWLMLTPPASS

Length  25

Organism  Phytolacca americana (American pokeweed) (Phytolacca decandra)

UniProt ID  Q40772,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03507.cif

Structure  SPKB03507.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2715.40674

Aliphatic index  136.4

Isoelectric point  9.537300927

Charge (pH=7)   0.999169354

Topological polar surface area  930.19

Aromaticity  0.04

Average rotatable bonds  3.52

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  36

X logP energy  -3.5745

Hydropathy 



Literature Information


Title  Characterization of translational inhibitors from Phytolacca americana. Amino-terminal sequence determination and antibody-inhibitor conjugates.

DOI  10.1016/0167-4838(84)90219-x,

Publication Year  1984

PubMed ID  6091760,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.