SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03495

Signal sequence   MKTPFEKIRIISCILVIVSTNVVG

Length  24

Organism  Bombyx mori (Silk moth)

UniProt ID  Q2VG86,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03495.cif

Structure  SPKB03495.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2661.30024

Aliphatic index  145.8333333

Isoelectric point  9.673754512

Charge (pH=7)   1.937191327

Topological polar surface area  999.08

Aromaticity  0.041666667

Average rotatable bonds  3.708333333

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  36

X logP energy  -6.47983

Hydropathy 



Literature Information


Title  A Sp?tzle-processing enzyme required for toll signaling activation in Drosophila innate immunity.

DOI  10.1016/j.devcel.2005.11.013,

Publication Year  2006

PubMed ID  16399077,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.