SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03493

Signal sequence   MRTLWIMAVLLLGVEG

Length  16

Organism  Protobothrops mucrosquamatus (Taiwan habu) (Trimeresurus mucrosquamatus)

UniProt ID  Q2PWA3,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03493.cif

Structure  SPKB03493.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1802.26654

Aliphatic index  164.375

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  635.04

Aromaticity  0.0625

Average rotatable bonds  3.6875

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  22

X logP energy  -0.76543

Hydropathy 



Literature Information


Title  Purification, characterization and cytokine release function of a novel Arg-49 phospholipase A(2) from the venom of Protobothrops mucrosquamatus.

DOI  10.1016/j.biochi.2006.05.003,

Publication Year  2006

PubMed ID  16793192,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.