General Information
SPKB ID SPKB03491
Signal sequence MRTLWIMAVLLVGVEG
Length 16
Organism Bothrops erythromelas (Caatinga lance head)
UniProt ID Q2HZ28,
Motif 1..16
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03491.cif
Physicochemical Information
Molecular weight 1788.23974
Aliphatic index 158.125
Isoelectric point 6.410149741
Charge (pH=7) -0.000243889
Topological polar surface area 635.04
Aromaticity 0.0625
Average rotatable bonds 3.625
Number of hydrogen bond donors 23
Number of hydrogen bond acceptors 22
X logP energy -1.15553
Hydropathy
Literature Information
Title BE-I-PLA2, a novel acidic phospholipase A2 from Bothrops erythromelas venom: isolation, cloning and characterization as potent anti-platelet and inductor of prostaglandin I2 release by endothelial cells.
DOI 10.1016/j.bcp.2006.04.032,
Publication Year 2006
PubMed ID 16750518,
Patent ID NA,