SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03486

Signal sequence   MLAGRGARAGGGLPRGWTALCLLSLLPFGFTNT

Length  33

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  Q28270,

Motif  1..33



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03486.cif

Structure  SPKB03486.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3376.00054

Aliphatic index  94.84848485

Isoelectric point  12.19926402

Charge (pH=7)   2.93599965

Topological polar surface area  1302.44

Aromaticity  0.090909091

Average rotatable bonds  3.181818182

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  44

X logP energy  -12.56139

Hydropathy 



Literature Information


Title  Canine CD34: cloning of the cDNA and evaluation of an antiserum to recombinant protein.

DOI  NA,

Publication Year  1996

PubMed ID  8822918,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.