SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03484

Signal sequence   MHLRIHARRNPPRRPAWTLGIWSLFWGCIVSSVWS

Length  35

Organism  Bos taurus (Bovine)

UniProt ID  Q28143,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03484.cif

Structure  SPKB03484.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4187.95054

Aliphatic index  89.14285714

Isoelectric point  12.67614624

Charge (pH=7)   5.117811209

Topological polar surface area  1600.61

Aromaticity  0.142857143

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  61

Number of hydrogen bond acceptors  51

X logP energy  -10.41375

Hydropathy 



Literature Information


Title  Conserved domain structure of beta-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins.

DOI  NA,

Publication Year  1994

PubMed ID  8163501,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.