General Information
SPKB ID SPKB03483
Signal sequence MGKLIRMGAQERRSLWPKRLHWSRPLFLLGMLIIGSTYQYLTSPQGLPTLWAAVSSQHPVKVASR
Length 65
Organism Bos taurus (Bovine)
UniProt ID Q28139,
Motif 1..65
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB03483.cif
Physicochemical Information
Molecular weight 7417.81994
Aliphatic index 97.53846154
Isoelectric point 12.23761872
Charge (pH=7) 8.178971806
Topological polar surface area 2888.38
Aromaticity 0.092307692
Average rotatable bonds 3.676923077
Number of hydrogen bond donors 104
Number of hydrogen bond acceptors 97
X logP energy -22.75548
Hydropathy 
Literature Information
Title The retinal rod Na(+)/Ca(2+),K(+) exchanger contains a noncleaved signal sequence required for translocation of the N terminus.
Publication Year 1999
PubMed ID 10608890,
Patent ID NA,
