SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03480

Signal sequence   MDISFLVFITLSMALFSSNVTGTSVTSRVRR

Length  31

Organism  Tachypleus tridentatus (Japanese horseshoe crab)

UniProt ID  Q27083,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03480.cif

Structure  SPKB03480.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3437.03284

Aliphatic index  103.5483871

Isoelectric point  12.19913391

Charge (pH=7)   1.99842085

Topological polar surface area  1404.71

Aromaticity  0.096774194

Average rotatable bonds  3.64516129

Number of hydrogen bond donors  53

Number of hydrogen bond acceptors  49

X logP energy  -15.70069

Hydropathy 



Literature Information


Title  Horseshoe crab (1,3)-beta-D-glucan-sensitive coagulation factor G. A serine protease zymogen heterodimer with similarities to beta-glucan-binding proteins.

DOI  NA,

Publication Year  1994

PubMed ID  8288603,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.