SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03476

Signal sequence   MKLLLLLIVSASMLIESLVNA

Length  21

Organism  Leiurus hebraeus (Hebrew deathstalker scorpion) (Leiurus quinquestriatus hebraeus)

UniProt ID  Q26292,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03476.cif

Structure  SPKB03476.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2271.88584

Aliphatic index  204.2857143

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  812.42

Aromaticity  0

Average rotatable bonds  3.761904762

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -2.7867

Hydropathy 



Literature Information


Title  Functional duality and structural uniqueness of depressant insect-selective neurotoxins.

DOI  10.1021/bi00233a025,

Publication Year  1991

PubMed ID  2029523,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.