SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03474

Signal sequence   MIIKALAIVSLCLASIQA

Length  18

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  Q23997,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03474.cif

Structure  SPKB03474.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1858.37144

Aliphatic index  190

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  667.59

Aromaticity  0

Average rotatable bonds  3.5

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -3.2398

Hydropathy 



Literature Information


Title  An abundantly secreted glycoprotein from Drosophila melanogaster is related to mammalian secretory proteins produced in rheumatoid tissues and by activated macrophages.

DOI  10.1016/0378-1119(94)00756-i,

Publication Year  1995

PubMed ID  7875581,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.