SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03471

Signal sequence   MASKSLVVLSACIIIGSA

Length  18

Organism  Lonomia obliqua (Moth)

UniProt ID  Q1HLC0,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03471.cif

Structure  SPKB03471.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1763.18404

Aliphatic index  157.2222222

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  664.96

Aromaticity  0

Average rotatable bonds  3.277777778

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -6.3454

Hydropathy 



Literature Information


Title  Losac, the first hemolin that exhibits procogulant activity through selective factor X proteolytic activation.

DOI  10.1074/jbc.M110.167718,

Publication Year  2011

PubMed ID  21177860,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.