SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03469

Signal sequence   MAPLCPSPWLPLLIPAPAPGLTVQLLLSLLLLVPVHP

Length  37

Organism  Homo sapiens (Human)

UniProt ID  Q16790,

Motif  1..37



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03469.cif

Structure  SPKB03469.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3891.90174

Aliphatic index  168.6486486

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  1180.06

Aromaticity  0.027027027

Average rotatable bonds  2.891891892

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  45

X logP energy  -0.3311

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.