SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03466

Signal sequence   MKISVAAIPFFLLITIALG

Length  19

Organism  Homo sapiens (Human)

UniProt ID  Q16627,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03466.cif

Structure  SPKB03466.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2018.57184

Aliphatic index  174.7368421

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  644.81

Aromaticity  0.105263158

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  24

X logP energy  0.0413

Hydropathy 



Literature Information


Title  Posttranslationally processed forms of the human chemokine HCC-1.

DOI  10.1021/bi992488q,

Publication Year  2000

PubMed ID  10978165,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.