SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03464

Signal sequence   MESSRVRLLPLLGAALLLMLPLLGTRA

Length  27

Organism  Homo sapiens (Human)

UniProt ID  Q16568,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03464.cif

Structure  SPKB03464.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2905.64014

Aliphatic index  166.2962963

Isoelectric point  12.19913393

Charge (pH=7)   1.999749488

Topological polar surface area  1086.03

Aromaticity  0

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  37

X logP energy  -6.01879

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.