General Information
SPKB ID SPKB03463
Signal sequence MTPGKTSLVSLLLLLSLEAIVKA
Length 23
Organism Homo sapiens (Human)
UniProt ID Q16552,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 5N7W,
Predicted Structure ID SPKB03463.cif
Physicochemical Information
Molecular weight 2397.98294
Aliphatic index 169.5652174
Isoelectric point 9.537300927
Charge (pH=7) 0.999169354
Topological polar surface area 885.22
Aromaticity 0
Average rotatable bonds 3.52173913
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 33
X logP energy -5.4635
Hydropathy
Literature Information
Title Signal peptide prediction based on analysis of experimentally verified cleavage sites.
DOI 10.1110/ps.04682504,
Publication Year 2004
PubMed ID 15340161,
Patent ID NA,