SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB03460

Signal sequence   MGPPHSGPGGVRVGALLLLGVLGLVSG

Length  27

Organism  Homo sapiens (Human)

UniProt ID  Q15768,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB03460.cif

Structure  SPKB03460.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2511.02374

Aliphatic index  133.3333333

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  924.59

Aromaticity  0

Average rotatable bonds  2.851851852

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  33

X logP energy  -8.53983

Hydropathy 



Literature Information


Title  Signal peptide prediction based on analysis of experimentally verified cleavage sites.

DOI  10.1110/ps.04682504,

Publication Year  2004

PubMed ID  15340161,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.